The CW has released an official description of the episode
7.22 – “There Will Be Blood“. Airs: Friday, May 11th, 2012 at 9/8c

SAM AND DEAN SEEK OUT AN ALPHA — In order to defeat Dick Roman (James Patrick Stuart) and the Leviathans, Sam (Jared Padalecki) and Dean (Jensen Ackles) must locate three key items. Castiel (Misha Collins) helps with one but for the last objects, the Winchesters must face two of their strongest opponents – an Alpha Vampire (Rick Worthy) and Crowley (Mark Sheppard). Meanwhile, Bobby (Jim Beaver) tries out a new ghost trick that ends up being very dangerous.

Written by: Andrew Dabb & Daniel Loflin, Directed by: Guy Bee

Source: The CW